The National Research Center for Transgenic Mouse (NRCTM) is the first center for commercial production of genetically engineered mouse. The NRCTM has been established at the National Institute for Genetic Engineering and Biotechnology (NIGEB) by the financial supports of the Vice Presidency for Science and Technology of I. R. IRAN at 2010. The center has been equipped with exceptional facilities for the production of transgenic and gene-targeted mice.